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Douglas Alexander MP, Labour's Shadow Foreign Secretary, commenting on Kofi Annan's resignation, said:
"Kofi Annan's resignation is the latest sign of the frustration and despair felt by so many in the face of the ongoing failure of the international community to bring an end to the violence in Syria.
"He deserves our gratitude and respect for the way he took on such a difficult and harrowing task with such dignity and determination.
"This latest setback must not be an excuse for inaction, but instead demands a new diplomatic effort to end this conflict which has already gone on too long and cost too many innocent lives.
"If the international community is to live up its responsibility, it must come together now otherwise the conflict will continue long after the battle now raging in Aleppo has ended."